Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.
Jin G, Zheng SL, Lilja H et al.
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Abstract
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Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood. Physiological and pathological factors have been shown to influence the %fPSA value and diagnostic accuracy.
3,192 European ancestry individuals
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