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GWAS Study

Genome-wide association study of body mass index in 23 000 individuals with and without asthma.

Melén E, Granell R, Kogevinas M et al.

23517042 PubMed ID
GWAS Study Type
14976 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ME
Melén E
GR
Granell R
KM
Kogevinas M
SD
Strachan D
GJ
Gonzalez JR
WM
Wjst M
JD
Jarvis D
EM
Ege M
BC
Braun-Fahrländer C
GJ
Genuneit J
HE
Horak E
BE
Bouzigon E
DF
Demenais F
KF
Kauffmann F
SV
Siroux V
MS
Michel S
VB
von Berg A
HA
Heinzmann A
KM
Kabesch M
PN
Probst-Hensch NM
CI
Curjuric I
IM
Imboden M
RT
Rochat T
HJ
Henderson J
SJ
Sterne JA
MW
McArdle WL
HJ
Hui J
JA
James AL
WM
William Musk A
PL
Palmer LJ
BA
Becker A
KA
Kozyrskyj AL
CM
Chan-Young M
PJ
Park JE
LA
Leung A
DD
Daley D
FM
Freidin MB
DI
Deev IA
OL
Ogorodova LM
PV
Puzyrev VP
CJ
Celedón JC
BJ
Brehm JM
CM
Cloutier MM
CG
Canino G
AE
Acosta-Pérez E
SM
Soto-Quiros M
AL
Avila L
BA
Bergström A
MJ
Magnusson J
SC
Söderhäll C
KI
Kull I
SS
Scholtens S
MB
Marike Boezen H
KG
Koppelman GH
WA
Wijga AH
MI
Marenholz I
EJ
Esparza-Gordillo J
LS
Lau S
LY
Lee YA
SM
Standl M
TC
Tiesler CM
FC
Flexeder C
HJ
Heinrich J
MR
Myers RA
OC
Ober C
ND
Nicolae DL
FM
Farrall M
KA
Kumar A
MM
Moffatt MF
CW
Cookson WO
LJ
Lasky-Su J
Chapter II

Abstract

Summary of the research findings

Both asthma and obesity are complex disorders that are influenced by environmental and genetic factors. Shared genetic factors between asthma and obesity have been proposed to partly explain epidemiological findings of co-morbidity between these conditions.

6,025 European ancestry children, 567 children, 6,334 European ancestry adult individuals, 2,050 adult individuals

Chapter III

Study Statistics

Key metrics and study information

14976
Total Participants
GWAS
Study Type
Yes
Replicated
979 European ancestry children, 921 Hispanic children, 120 children
Replication Participants
European, Other, Hispanic or Latin American
Ancestry
Sweden, Australia, Germany, U.K., Switzerland, Austria, France, Russian Federation, Netherlands, Canada, U.S., Puerto Rico, Costa Rica
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.