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GWAS Study

Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.

Gelernter J, Kranzler HR, Sherva R et al.

24143882 PubMed ID
GWAS Study Type
12309 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GJ
Gelernter J
KH
Kranzler HR
SR
Sherva R
KR
Koesterer R
AL
Almasy L
ZH
Zhao H
FL
Farrer LA
Chapter II

Abstract

Summary of the research findings

We report a genome-wide association study (GWAS) of two populations, African-American and European-American (AA, EA) for opioid dependence (OD) in three sets of subjects, to identify pathways, genes, and alleles important in OD risk.

1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African American controls

Chapter III

Study Statistics

Key metrics and study information

12309
Total Participants
GWAS
Study Type
Yes
Replicated
2,116 European ancestry individuals, 4,496 African American individuals
Replication Participants
European, African American or Afro-Caribbean
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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