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GWAS Study

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.

Xu W, Cohen-Woods S, Chen Q et al.

24387768 PubMed ID
GWAS Study Type
2451 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

XW
Xu W
CS
Cohen-Woods S
CQ
Chen Q
NA
Noor A
KJ
Knight J
HG
Hosang G
PS
Parikh SV
DL
De Luca V
TF
Tozzi F
MP
Muglia P
FJ
Forte J
MA
McQuillin A
HP
Hu P
GH
Gurling HM
KJ
Kennedy JL
MP
McGuffin P
FA
Farmer A
SJ
Strauss J
VJ
Vincent JB
Chapter II

Abstract

Summary of the research findings

Recently, genome-wide association studies (GWAS) for cases versus controls using single nucleotide polymorphism microarray data have shown promising findings for complex neuropsychiatric disorders, including bipolar disorder (BD).

912 European ancestry cases, 903 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2451
Total Participants
GWAS
Study Type
Yes
Replicated
636 individuals from 224 trios
Replication Participants
European
Ancestry
Canada, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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