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GWAS Study

Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study.

Frau F, Zaninello R, Salvi E et al.

25410890 PubMed ID
GWAS Study Type
588 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FF
Frau F
ZR
Zaninello R
SE
Salvi E
OM
Ortu MF
BD
Braga D
VD
Velayutham D
AG
Argiolas G
FG
Fresu G
TC
Troffa C
BE
Bulla E
BP
Bulla P
PS
Pitzoi S
PD
Piras DA
GV
Glorioso V
CM
Chittani M
BG
Bernini G
BM
Bardini M
FF
Fallo F
ML
Malatino L
SB
Stancanelli B
RG
Regolisti G
FC
Ferri C
DG
Desideri G
SG
Scioli GA
GF
Galletti F
SA
Sciacqua A
PF
Perticone F
DE
Degli Esposti E
SA
Sturani A
SA
Semplicini A
VF
Veglio F
MP
Mulatero P
WT
Williams TA
LC
Lanzani C
HT
Hiltunen TP
KK
Kontula K
BE
Boerwinkle E
TS
Turner ST
MP
Manunta P
BC
Barlassina C
CD
Cusi D
GN
Glorioso N
Chapter II

Abstract

Summary of the research findings

Essential hypertension arises from the combined effect of genetic and environmental factors. A pharmacogenomics approach could help to identify additional molecular mechanisms involved in its pathogenesis.

372 European ancestry hypertensive individuals

Chapter III

Study Statistics

Key metrics and study information

588
Total Participants
GWAS
Study Type
Yes
Replicated
216 European ancestry hypertensive individuals
Replication Participants
European
Ancestry
Italy
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.