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GWAS Study

A genome-wide association study of chronic obstructive pulmonary disease in Hispanics.

Chen W, Brehm JM, Manichaikul A et al.

25584925 PubMed ID
GWAS Study Type
1525 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CW
Chen W
BJ
Brehm JM
MA
Manichaikul A
CM
Cho MH
BN
Boutaoui N
YQ
Yan Q
BK
Burkart KM
EP
Enright PL
RJ
Rotter JI
PH
Petersen H
LS
Leng S
OM
Obeidat M
BY
Bossé Y
BC
Brandsma CA
HK
Hao K
RS
Rich SS
PR
Powell R
AL
Avila L
SM
Soto-Quiros M
SE
Silverman EK
TY
Tesfaigzi Y
BR
Barr RG
CJ
Celedón JC
Chapter II

Abstract

Summary of the research findings

Rationale: Genome-wide association studies (GWAS) of chronic obstructive pulmonary disease (COPD) have identified disease-susceptibility loci, mostly in subjects of European descent.

94 Costa Rican founder population smoker cases, 412 Costa Rican founder population smoker controls, 63 Hispanic ancestry cases, 619 Hispanic ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1525
Total Participants
GWAS
Study Type
Yes
Replicated
47 Hispanic ancestry smoker cases, 290 Hispanic ancestry smoker controls
Replication Participants
Hispanic or Latin American
Ancestry
U.S., Costa Rica
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.