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GWAS Study

Identification of novel genetic markers of breast cancer survival.

Guo Q, Schmidt MK, Kraft P et al.

25890600 PubMed ID
GWAS Study Type
37954 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GQ
Guo Q
SM
Schmidt MK
KP
Kraft P
CS
Canisius S
CC
Chen C
KS
Khan S
TJ
Tyrer J
BM
Bolla MK
WQ
Wang Q
DJ
Dennis J
MK
Michailidou K
LM
Lush M
KS
Kar S
BJ
Beesley J
DA
Dunning AM
SM
Shah M
CK
Czene K
DH
Darabi H
EM
Eriksson M
LD
Lambrechts D
WC
Weltens C
LK
Leunen K
BS
Bojesen SE
NB
Nordestgaard BG
NS
Nielsen SF
FH
Flyger H
CJ
Chang-Claude J
RA
Rudolph A
SP
Seibold P
FD
Flesch-Janys D
BC
Blomqvist C
AK
Aittomäki K
FR
Fagerholm R
MT
Muranen TA
CF
Couch FJ
OJ
Olson JE
VC
Vachon C
AI
Andrulis IL
KJ
Knight JA
GG
Glendon G
MA
Mulligan AM
BA
Broeks A
HF
Hogervorst FB
HC
Haiman CA
HB
Henderson BE
SF
Schumacher F
LM
Le Marchand L
HJ
Hopper JL
TH
Tsimiklis H
AC
Apicella C
SM
Southey MC
CA
Cox A
CS
Cross SS
RM
Reed MW
GG
Giles GG
MR
Milne RL
MC
McLean C
WR
Winqvist R
PK
Pylkäs K
JA
Jukkola-Vuorinen A
GM
Grip M
HM
Hooning MJ
HA
Hollestelle A
MJ
Martens JW
VD
van den Ouweland AM
MF
Marme F
SA
Schneeweiss A
YR
Yang R
BB
Burwinkel B
FJ
Figueroa J
CS
Chanock SJ
LJ
Lissowska J
SE
Sawyer EJ
TI
Tomlinson I
KM
Kerin MJ
MN
Miller N
BH
Brenner H
DA
Dieffenbach AK
AV
Arndt V
HB
Holleczek B
MA
Mannermaa A
KV
Kataja V
KV
Kosma VM
HJ
Hartikainen JM
LJ
Li J
BJ
Brand JS
HK
Humphreys K
DP
Devilee P
TR
Tollenaar RA
SC
Seynaeve C
RP
Radice P
PP
Peterlongo P
BB
Bonanni B
MP
Mariani P
FP
Fasching PA
BM
Beckmann MW
HA
Hein A
EA
Ekici AB
CG
Chenevix-Trench G
BR
Balleine R
PK
Phillips KA
BJ
Benitez J
ZM
Zamora MP
AP
Arias Perez JI
MP
Menéndez P
JA
Jakubowska A
LJ
Lubinski J
JK
Jaworska-Bieniek K
DK
Durda K
HU
Hamann U
KM
Kabisch M
UH
Ulmer HU
RT
Rüdiger T
MS
Margolin S
KV
Kristensen V
NS
Nord S
ED
Evans DG
AJ
Abraham JE
EH
Earl HM
HL
Hiller L
DJ
Dunn JA
BS
Bowden S
BC
Berg C
CD
Campa D
DW
Diver WR
GS
Gapstur SM
GM
Gaudet MM
HS
Hankinson SE
HR
Hoover RN
HA
Hüsing A
KR
Kaaks R
MM
Machiela MJ
WW
Willett W
BM
Barrdahl M
CF
Canzian F
CS
Chin SF
CC
Caldas C
HD
Hunter DJ
LS
Lindstrom S
GM
García-Closas M
HP
Hall P
ED
Easton DF
ED
Eccles DM
RN
Rahman N
NH
Nevanlinna H
PP
Pharoah PD
Chapter II

Abstract

Summary of the research findings

Survival after a diagnosis of breast cancer varies considerably between patients, and some of this variation may be because of germline genetic variation. We aimed to identify genetic markers associated with breast cancer-specific survival.

23,059 European ancestry estrogen-receptor positive cases, 6,881 European ancestry estrogen-receptor negative cases, 8,014 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

37954
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Finland, Sweden, U.S., Australia, Netherlands, Canada, Belgium, Germany, U.K., Republic of Ireland, Denmark
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.