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GWAS Study

Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy.

Khan S, Fagerholm R, Rafiq S et al.

25964295 PubMed ID
GWAS Study Type
4011 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KS
Khan S
FR
Fagerholm R
RS
Rafiq S
TW
Tapper W
AK
Aittomäki K
LJ
Liu J
BC
Blomqvist C
ED
Eccles D
NH
Nevanlinna H
Chapter II

Abstract

Summary of the research findings

Purpose: Although most patients with estrogen receptor (ER)-positive breast cancer benefit from endocrine therapies, a significant proportion do not. Our aim was to identify inherited genetic variations that might predict survival among patients receiving adjuvant endocrine therapies.

639 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

4011
Total Participants
GWAS
Study Type
Yes
Replicated
3,372 European ancestry cases
Replication Participants
European
Ancestry
Finland, U.K., Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.