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GWAS Study

Genome-wide association study of pathological gambling.

Lang M, Leménager T, Streit F et al.

27315593 PubMed ID
GWAS Study Type
1431 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LM
Lang M
LT
Leménager T
SF
Streit F
FM
Fauth-Bühler M
FJ
Frank J
JD
Juraeva D
WS
Witt SH
DF
Degenhardt F
HA
Hofmann A
HS
Heilmann-Heimbach S
KF
Kiefer F
BB
Brors B
GH
Grabe HJ
JU
John U
BA
Bischof A
BG
Bischof G
VU
Völker U
HG
Homuth G
BM
Beutel M
LP
Lind PA
MS
Medland SE
SW
Slutske WS
MN
Martin NG
VH
Völzke H
NM
Nöthen MM
MC
Meyer C
RH
Rumpf HJ
WF
Wurst FM
RM
Rietschel M
MK
Mann KF
Chapter II

Abstract

Summary of the research findings

Pathological gambling is a behavioural addiction with negative economic, social, and psychological consequences. Identification of contributing genes and pathways may improve understanding of aetiology and facilitate therapy and prevention. Here, we report the first genome-wide association study of pathological gambling. Our aims were to identify pathways involved in pathological gambling, and examine whether there is a genetic overlap between pathological gambling and alcohol dependence.

445 European ancestry cases, 986 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1431
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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