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GWAS Study

Genome-wide association studies in non-anxiety individuals identified novel risk loci for depression.

Cheng B, Qi X, Meng P et al.

35730328 PubMed ID
GWAS Study Type
79139 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CB
Cheng B
QX
Qi X
MP
Meng P
CS
Cheng S
YX
Yang X
LL
Liu L
YY
Yao Y
JY
Jia Y
WY
Wen Y
ZF
Zhang F
Chapter II

Abstract

Summary of the research findings

Depression is a debilitating mental disorder that often coexists with anxiety. The genetic mechanisms of depression and anxiety have considerable overlap, and studying depression in non-anxiety samples could help to discover novel gene. We assess the genetic variation of depression in non-anxiety samples, using genome-wide association studies (GWAS) and linkage disequilibrium score regression (LDSC).

59,334 European ancestry cases, 19,805 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

79139
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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