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GWAS Study

Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.

Shadrin AA, Smeland OB, Zayats T et al.

29413154 PubMed ID
GWAS Study Type
338460 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SA
Shadrin AA
SO
Smeland OB
ZT
Zayats T
SA
Schork AJ
FO
Frei O
BF
Bettella F
WA
Witoelar A
LW
Li W
EJ
Eriksen JA
KF
Krull F
DS
Djurovic S
FS
Faraone SV
RT
Reichborn-Kjennerud T
TW
Thompson WK
JS
Johansson S
HJ
Haavik J
DA
Dale AM
WY
Wang Y
AO
Andreassen OA
Chapter II

Abstract

Summary of the research findings

Objective: Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable psychiatric condition. By exploiting the reported relationship between ADHD and educational attainment (EA), we aimed to improve discovery of ADHD-associated genetic variants and to investigate genetic overlap between these phenotypes.

2,064 European and unknown ancestry ADHD trios, 896 European and unknown ancestry ADHD cases, 2,455 European and unknown ancestry controls, 328,917 European ancestry individuals with educational attainment data

Chapter III

Study Statistics

Key metrics and study information

338460
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., Germany, Israel, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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