Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient.
Mychaleckyj JC, Nayak U, Colgate ER et al.
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Abstract
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Breast milk is the sole nutrition source during exclusive breastfeeding, and polyunsaturated fatty acids (FAs) are critical micronutrients in infant physical and cognitive development. There has been no prior genomewide association study of breast milk, hence our objective was to test for genetic association with breast milk FA composition.
1,142 Bangladeshi ancestry (non-array genotyped, whole-genome imputed) mothers
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