Genome-wide analysis of genetic determinants of circulating factor VII activating protease (FSAP) activity.
Olsson M, Stanne TM, Pedersen A et al.
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Abstract
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Essentials Knowledge of genetic regulators of plasma factor VII activating protease (FSAP) levels is limited. We performed a genome-wide analysis of variants influencing FSAP activity in Scandinavian cohorts. We replicated an association for Marburg-1 and identified an association for a HABP2 stop variant. We identified a novel locus near ADCY2 as a potential additional regulator of FSAP activity.
3,126 Swedish ancestry individuals
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