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GWAS Study

Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.

Trajanoska K, Morris JA, Oei L et al.

30158200 PubMed ID
GWAS Study Type
562258 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TK
Trajanoska K
MJ
Morris JA
OL
Oei L
ZH
Zheng HF
ED
Evans DM
KD
Kiel DP
OC
Ohlsson C
RJ
Richards JB
RF
Rivadeneira F
Chapter II

Abstract

Summary of the research findings

Objectives: To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk.

37,857 European or East Asian cases, 227,116 European or East Asian controls

Chapter III

Study Statistics

Key metrics and study information

562258
Total Participants
GWAS
Study Type
Yes
Replicated
147,200 European ancestry cases, 150,085 European ancestry controls
Replication Participants
East Asian, European, Other
Ancestry
China, Hong Kong SAR, U.S., Australia, Netherlands, Estonia, Finland, Iceland, Republic of Ireland, Sweden, U.K., Canada, Austria, France, Poland, Denmark, Greece, Italy, Malta, Slovenia, Spain, Russian Federation, Republic of Korea
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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