Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone.
Popović M, Matana A, Torlak V et al.
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Abstract
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Purpose: Thyroid hormones are essential for the normal function of almost all human tissues, and have critical roles in metabolism, differentiation and growth. Free triiodothyronine (fT3), free thyroxine (fT4) and thyroid-stimulating hormone (TSH) levels are under strong genetic influence; however, most of the heritability is yet unexplained.
629 Croatian individuals, 510 Korculan (founder/genetic isolate) individuals, 590 Vis (founder/genetic isolate) individuals
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