Genome-wide association analysis suggests novel loci for Hashimoto's thyroiditis.
Brčić L, Barić A, Gračan S et al.
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Abstract
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Purpose: Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid diseases. Current knowledge of HT genetics is limited, and not a single genome-wide association study (GWAS) focusing exclusively on HT has been performed to date. In order to decipher genetic determinants of HT, we performed the first GWAS followed by replication in a total of 1443 individuals from Croatia.
405 Croatian ancestry cases, 433 Croatian ancestry controls
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