Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9.
Thorp JG, Marees AT, Ong JS et al.
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Abstract
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Depression is a clinically heterogeneous disorder. Previous large-scale genetic studies of depression have explored genetic risk factors of depression case-control status or aggregated sums of depressive symptoms, ignoring possible clinical or genetic heterogeneity.
32,263 European ancestry cases, 116,489 European ancestry controls
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