Pilot GWAS of caries in African-Americans shows genetic heterogeneity.
Orlova E, Carlson JC, Lee MK et al.
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Abstract
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Dental caries is the most common chronic disease in the US and disproportionately affects racial/ethnic minorities. Caries is heritable, and though genetic heterogeneity exists between ancestries for a substantial portion of loci associated with complex disease, a genome-wide association study (GWAS) of caries specifically in African Americans has not been performed previously.
109 African American adults
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