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GWAS Study

Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children.

Mateos MK, Tulstrup M, Quinn MC et al.

32438682 PubMed ID
GWAS Study Type
1573 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MM
Mateos MK
TM
Tulstrup M
QM
Quinn MC
TR
Tuckuviene R
MG
Marshall GM
GR
Gupta R
MC
Mayoh C
WB
Wolthers BO
BP
Barbaro PM
RE
Ruud E
SR
Sutton R
HP
Huttunen P
RT
Revesz T
TS
Trakymiene SS
BD
Barbaric D
TU
Tedgård U
GJ
Giles JE
AF
Alvaro F
JO
Jonsson OG
MF
Mechinaud F
SK
Saks K
CD
Catchpoole D
KR
Kotecha RS
DL
Dalla-Pozza L
CG
Chenevix-Trench G
TT
Trahair TN
MS
MacGregor S
SK
Schmiegelow K
Chapter II

Abstract

Summary of the research findings

Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lymphoblastic leukemia (ALL), but whether a genetic predisposition exists across different ALL treatment regimens has not been well studied.

92 European ancestry cases, 1,481 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1573
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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