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GWAS Study

Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.

Keene KL, Hyacinth HI, Bis JC et al.

32693751 PubMed ID
GWAS Study Type
22051 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KK
Keene KL
HH
Hyacinth HI
BJ
Bis JC
KS
Kittner SJ
MB
Mitchell BD
CY
Cheng YC
PG
Pare G
CM
Chong M
OM
O'Donnell M
MJ
Meschia JF
CW
Chen WM
SM
Sale MM
RS
Rich SS
NM
Nalls MA
ZA
Zonderman AB
EM
Evans MK
WJ
Wilson JG
CA
Correa A
MH
Markus HS
TM
Traylor M
LC
Lewis CM
CC
Carty CL
RA
Reiner A
HJ
Haessler J
LC
Langefeld CD
GR
Gottesman R
MT
Mosley TH
WD
Woo D
YK
Yaffe K
LY
Liu Y
LW
Longstreth WT
PB
Psaty BM
KC
Kooperberg C
LL
Lange LA
SR
Sacco R
RT
Rundek T
LJ
Lee JM
CC
Cruchaga C
FK
Furie KL
AD
Arnett DK
BO
Benavente OR
GR
Grewal RP
PL
Peddareddygari LR
DM
Dichgans M
MR
Malik R
WB
Worrall BB
FM
Fornage M
Chapter II

Abstract

Summary of the research findings

Background and purpose: Stroke is a complex disease with multiple genetic and environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to 3× more likely to die from stroke than European Americans.

3,734 African ancestry cases, 18,317 African ancestry controls

Chapter III

Study Statistics

Key metrics and study information

22051
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, African unspecified
Ancestry
U.K., Canada, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.