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GWAS Study

Association of Genetic Polymorphisms With Hepatitis C Virus-related Liver Cirrhosis in Japan.

Kamimura S, Tamura A, Ishii T et al.

33144438 PubMed ID
GWAS Study Type
3859 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KS
Kamimura S
TA
Tamura A
IT
Ishii T
KT
Kanda T
MM
Moriyama M
Chapter II

Abstract

Summary of the research findings

Background/aim: Hepatitis C virus (HCV) infection is an important health problem in the direct-acting antivirals-era. HCV causes life-threatening diseases, such as cirrhosis and hepatocellular carcinoma. Our aim was to examine whether certain single-nucleotide polymorphisms (SNPs) are associated with the prevalence of HCV infections progressing to cirrhosis in the Japanese population by a genome-wide association study-based approach.

195 Japanese ancestry cases, 1,553 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3859
Total Participants
GWAS
Study Type
Yes
Replicated
753 Japanese ancestry cases, 1,358 Japanese ancestry controls
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.