A genome-wide association meta-analysis identifies new Eosinophilic esophagitis loci.
Chang X, March M, Mentch F et al.
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Abstract
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Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus marked by eosinophilic infiltration. Cumulative evidence indicates that the risk of EoE involves the complex interplay of both genetic and environmental factors. Because only a few genetic loci have been identified in EoE, the genetic underpinning of EoE remains largely elusive.
1,288 European ancestry male cases, 6,548 European ancestry male controls
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