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GWAS Study

High-density lipoprotein 3 cholesterol and primary open-angle glaucoma: metabolomics and mendelian randomization analyses.

Nusinovici S, Li H, Thakur S et al.

34592243 PubMed ID
GWAS Study Type
18341 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NS
Nusinovici S
LH
Li H
TS
Thakur S
BM
Baskaran M
TY
Tham YC
ZL
Zhou L
SC
Sabanayagam C
AT
Aung T
SD
Silver D
FQ
Fan Q
WT
Wong TY
CJ
Crowston J
CC
Cheng CY
Chapter II

Abstract

Summary of the research findings

Purpose: We hypothesized that the effect of blood lipid-related metabolites on primary open-angle glaucoma (POAG) would differ according to specific lipoprotein particles and lipid sub-fractions. We investigated the associations of blood levels of lipoprotein particles and lipid sub-fractions with POAG.

2,308 Chinese ancestry individuals, 2,528 Indian ancestry individuals, 2,521 Malays ancestry individuals, 10,984 Finnish ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

18341
Total Participants
GWAS
Study Type
No
Replicated
East Asian, South Asian, South East Asian, European
Ancestry
Singapore
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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