Active: Ophthalmology Clear all

GWAS 2022-04-28

Genome-wide Survival Analysis for Macular Neovascularization Development in Central Serous Chorioretinopathy Revealed Shared Genetic Susceptibility with Polypoidal Choroidal Vasculopathy.

Mori Y, Miyake M et al.

Ophthalmology

Purpose: To identify susceptibility genes for macular neovascularization (MNV) development in centra...

Macular neovascularization in central serous chorioretinopathy

Replicated

539

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-11

GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development.

Simcoe MJ, Shah A et al.

Ophthalmology

Purpose: To identify genetic variants associated with pigment dispersion syndrome (PDS) and pigmenta...

Pigment dispersion syndrome or pigmentary glaucoma

53201

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

High-density lipoprotein 3 cholesterol and primary open-angle glaucoma: metabolomics and mendelian randomization analyses.

Nusinovici S, Li H et al.

Ophthalmology

Purpose: We hypothesized that the effect of blood lipid-related metabolites on primary open-angle gl...

High-density lipoprotein 3 cholesterol levels

18341

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-16

Genome-wide association study in Asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis.

Meguro A, Yamane T et al.

Ophthalmology

Purpose: To identify novel susceptibility loci for high myopia.

High myopia

Replicated

14045

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-01

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.

Lorés-Motta L, Paun CC et al.

Ophthalmology

Purpose: To identify genetic variants associated with complement activation, which may help to selec...

Serum C3d:C3 ratio (systemic complement activation)

Replicated

2245

Participants

N/A

Studies

Details PubMed

GWAS 2012-06-15

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

Sobrin L, Ripke S et al.

Ophthalmology

Purpose: To investigate whether the 2 subtypes of advanced age-related macular degeneration (AMD), c...

Age-related macular degeneration (choroidal neovascularisation)

Replicated

25664

Participants

N/A

Studies

Details PubMed

GWAS 2011-02-08

Genome-wide association study of diabetic retinopathy in a Taiwanese population.

Huang YC, Lin JM et al.

Ophthalmology

Purpose: Diabetic retinopathy (DR) is a microvascular complication of diabetes with a complex multif...

Diabetic retinopathy

849

Participants

N/A

Studies

Details PubMed

GWAS 2010-11-20

Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese.

Li YJ, Goh L et al.

Ophthalmology

Objective: To determine susceptibility genes for high myopia in Singaporean Chinese.

Myopia (pathological)

Replicated

4067

Participants

N/A

Studies

Details PubMed

GWAS 2010-04-02

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.

Meguro A, Inoko H et al.

Ophthalmology

Purpose: Factors contributing to the development of normal tension glaucoma (NTG), degenerative opti...

Glaucoma

660

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide Survival Analysis for Macular Neovascularization Development in Central Serous Chorioretinopathy Revealed Shared Genetic Susceptibility with Polypoidal Choroidal Vasculopathy.

Mori Y, Miyake M et al.

Ophthalmology

Macular neovascularization in central serous chorioretinopathy

2022-04-28

GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development.

Simcoe MJ, Shah A et al.

Ophthalmology

Pigment dispersion syndrome or pigmentary glaucoma

2022-01-11

High-density lipoprotein 3 cholesterol and primary open-angle glaucoma: metabolomics and mendelian randomization analyses.

Nusinovici S, Li H et al.

Ophthalmology

High-density lipoprotein 3 cholesterol levels

2021-09-27

Genome-wide association study in Asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis.

Meguro A, Yamane T et al.

Ophthalmology

High myopia

2020-05-16

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.

Lorés-Motta L, Paun CC et al.

Ophthalmology

Serum C3d:C3 ratio (systemic complement activation)

2018-02-01

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

Sobrin L, Ripke S et al.

Ophthalmology

Age-related macular degeneration (choroidal neovascularisation)

2012-06-15

Genome-wide association study of diabetic retinopathy in a Taiwanese population.

Huang YC, Lin JM et al.

Ophthalmology

Diabetic retinopathy

2011-02-08

Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese.

Li YJ, Goh L et al.

Ophthalmology

Myopia (pathological)

2010-11-20

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.

Meguro A, Inoko H et al.

Ophthalmology

Glaucoma

2010-04-02