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GWAS Study

A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer.

Naderi E, Crijns APG, Steenbakkers RJHM et al.

34838041 PubMed ID
GWAS Study Type
1043 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NE
Naderi E
CA
Crijns APG
SR
Steenbakkers RJHM
VD
van den Hoek JGM
BH
Boezen HM
AB
Alizadeh BZ
LJ
Langendijk JA
Chapter II

Abstract

Summary of the research findings

Most head and neck cancer (HNC) patients receive radiotherapy (RT) and develop toxicities. This genome-wide association study (GWAS) was designed to identify single nucleotide polymorphisms (SNPs) associated with common acute radiation-induced toxicities (RITs) in an HNC cohort.

802 Dutch ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1043
Total Participants
GWAS
Study Type
Yes
Replicated
241 Dutch ancestry individuals
Replication Participants
European
Ancestry
Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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