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GWAS Study

Genome-wide Meta-analysis Identifies Novel Susceptibility Loci for Autoimmune Hepatitis Type 1.

Li Y, Sun Y, Liu Y et al.

35184318 PubMed ID
GWAS Study Type
12088 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LY
Li Y
SY
Sun Y
LY
Liu Y
WB
Wang B
LJ
Li J
WH
Wang H
ZH
Zhang H
WX
Wang X
HX
Han X
LQ
Lin Q
ZY
Zhou Y
HL
Hu L
SY
Song Y
BJ
Bao J
GL
Gong L
SM
Sun M
YX
Yuan X
ZX
Zhang X
LM
Lian M
XX
Xiao X
MQ
Miao Q
WQ
Wang Q
LK
Li KK
DS
Du S
MA
Ma A
LY
Li Y
XJ
Xu J
TS
Tang S
SJ
Shi J
XY
Xu Y
YL
Yang L
ZJ
Zhang J
HZ
Huang Z
ZL
Zhou L
CY
Cui Y
SM
Seldin MF
GM
Gershwin ME
YH
Yan H
ZZ
Zou Z
ZX
Zuo X
TR
Tang R
MX
Ma X
Chapter II

Abstract

Summary of the research findings

Background and aims: Autoimmune hepatitis (AIH) is a rare and chronic autoimmune liver disease. While genetic factors are believed to play a crucial role in the etiopathogenesis of AIH, our understanding of these genetic risk factors is still limited. In this study, we aimed to identify susceptibility loci to further understand the pathogenesis of this disease.

1,622 Han Chinese ancestry cases, 10,466 Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

12088
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.