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GWAS Study

Identification of novel genes influencing eosinophil-specific protein levels in asthma families.

Vernet R, Matran R, Zerimech F et al.

35671886 PubMed ID
GWAS Study Type
1171 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

VR
Vernet R
MR
Matran R
ZF
Zerimech F
MA
Madore AM
LM
Lavoie ME
GP
Gagnon PA
MH
Mohamdi H
MP
Margaritte-Jeannin P
SV
Siroux V
DM
Dizier MH
DF
Demenais F
LC
Laprise C
NR
Nadif R
BE
Bouzigon E
Chapter II

Abstract

Summary of the research findings

Eosinophils play a key role in the asthma allergic response by releasing cytotoxic molecules such as eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) that generate epithelium damages.

1,018 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1171
Total Participants
GWAS
Study Type
Yes
Replicated
153 French-Canadian founder ancestry individuals
Replication Participants
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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