Candidate loci shared among periodontal disease, diabetes and bone density.
Yu YH, Steffensen B, Ridker PM et al.
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Abstract
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Introduction: While periodontal disease (PD) has been associated with type 2 diabetes (T2D) and osteoporosis, the underlying genetic mechanisms for these associations remain largely unknown. The aim of this study is to apply cross-trait genetic analyses to investigate the potentially shared biology among PD, T2D, and bone mineral density (BMD) by assessing pairwise genetic correlations and searching for shared polymorphisms.
at least 506,594 individuals (MTAG boosted by type 2 diabetes samples)
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