A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.
Middha P, Wang X, Behrens S et al.
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Abstract
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Genome-wide studies of gene-environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures. We conducted a genome-wide G×E analysis of ~ 7.6 million common variants and seven lifestyle/environmental risk factors for breast cancer risk overall and for estrogen receptor positive (ER +) breast cancer.
72,285 European ancestry cases, 80,354 European ancestry controls
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