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GWAS Study

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L, Xu X et al.

39620209 PubMed ID
GWAS Study Type
190904 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LX
Lyu X
PL
Peng L
XX
Xu X
FY
Fan Y
YY
Yang Y
CJ
Chen J
LM
Liu M
CY
Chen Y
ZC
Zhang C
YS
Yang S
SS
Shen S
ZJ
Zhang J
ZX
Zeng X
SH
Shen H
LD
Luo D
LY
Lin Y
Chapter II

Abstract

Summary of the research findings

Purpose: Epidemiological studies have demonstrated the clinical link between Hunner interstitial cystitis (HIC) and autoimmune diseases (ADs), suggesting potential shared genetic bases for their comorbidity. We aimed to investigate the shared genetic architecture and causal relationships between HIC and ADs.

153 East Asian ancestry cystitis cases, 2,472 East Asian ancestry atopic dermatitis cases, 188,279 controls

Chapter III

Study Statistics

Key metrics and study information

190904
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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