Active: Allergic disease Clear all

GWAS 2024-04-01

Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population.

Kim JW, Kim MJ et al.

Ann Dermatol

Allergic diseases include atopic dermatitis (AD) and allergic rhinitis (AR), which are chronic, rela...

Allergic disease

8823

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-08

The genome-wide association study of serum IgE levels demonstrated the shared genetic background in allergic diseases.

Lu HF, Chou CH et al.

Clin Immunol

Immunoglobulin E (IgE) synthessis is highly related to a variety of atopic diseases, and several gen...

Serum IgE levels

Replicated

17884

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-20

A genome-wide association study for allergen component sensitizations identifies allergen component-specific and allergen protein group-specific associations.

Morii W, Kasai K et al.

J Allergy Clin Immunol Glob

Allergic diseases are some of the most common diseases worldwide. Genome-wide association studies (G...

Allergen component sensitization (Alnus glutinosa 1)

564

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-02

A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.

Chang D, Hunkapiller J et al.

Sci Rep

Genome-wide association studies (GWAS) have identified many common variant loci associated with asth...

Asthma (moderate or severe)

6771

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-15

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator.

Yamada M, Motoike IN et al.

Commun Biol

Lung function reflects the ability of the respiratory system and is utilized for the assessment of r...

Lung function (forced expiratory volume in 1 second)

Replicated

19722

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-01

Genome-wide association study identifies BTNL2 associated with atopic asthma in children.

Kim SY, Kim EG et al.

Medicine (Baltimore)

Asthma is a heterogeneous disease characterized by chronic airway inflammation with a genetic predis...

Atopic asthma

377

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-30

A cross-population atlas of genetic associations for 220 human phenotypes.

Sakaue S, Kanai M et al.

Nat Genet

Current genome-wide association studies do not yet capture sufficient diversity in populations and s...

Ulcerative colitis

178689

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

Many common and rare variants associated with hematologic traits have been discovered through imputa...

White blood cell count

Replicated

260928

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-15

Multi-ethnic genome-wide and HLA association study of total serum IgE.

Daya M, Cox C et al.

J Allergy Clin Immunol

Total serum IgE (tIgE) is an important intermediate phenotype of allergic disease. Whole genome gene...

IgE levels

21901

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-22

Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.

Margaritte-Jeannin P, Budu-Aggrey A et al.

Clin Exp Allergy

Numerous genes have been associated with the three most common allergic diseases (asthma, allergic r...

Asthma and eczema

8807

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-02

Eight novel susceptibility loci and putative causal variants in atopic dermatitis.

Tanaka N, Koido M et al.

J Allergy Clin Immunol

Atopic dermatitis (AD) is the most common allergic disease in the world. While genetic components pl...

Atopic dermatitis

113101

Participants

N/A

Studies

Details PubMed

GWAS 2020-07-07

Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories.

Gabryszewski SJ, Chang X et al.

J Allergy Clin Immunol

The allergic march refers to the natural history of allergic conditions during infancy and childhood...

Allergic march (atopic dermatitis to allergic rhinitis)

Replicated

2487

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population.

Kim JW, Kim MJ et al.

Ann Dermatol

Allergic disease

2024-04-01

The genome-wide association study of serum IgE levels demonstrated the shared genetic background in allergic diseases.

Lu HF, Chou CH et al.

Clin Immunol

Serum IgE levels

2024-01-08

A genome-wide association study for allergen component sensitizations identifies allergen component-specific and allergen protein group-specific associations.

Morii W, Kasai K et al.

J Allergy Clin Immunol Glob

Allergen component sensitization (Alnus glutinosa 1)

2023-02-20

A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.

Chang D, Hunkapiller J et al.

Sci Rep

Asthma (moderate or severe)

2022-04-02

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator.

Yamada M, Motoike IN et al.

Commun Biol

Lung function (forced expiratory volume in 1 second)

2021-11-15

Genome-wide association study identifies BTNL2 associated with atopic asthma in children.

Kim SY, Kim EG et al.

Medicine (Baltimore)

Atopic asthma

2021-11-01

A cross-population atlas of genetic associations for 220 human phenotypes.

Sakaue S, Kanai M et al.

Nat Genet

Ulcerative colitis

2021-09-30

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

White blood cell count

2021-09-27

Multi-ethnic genome-wide and HLA association study of total serum IgE.

Daya M, Cox C et al.

J Allergy Clin Immunol

IgE levels

2021-09-15

Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.

Margaritte-Jeannin P, Budu-Aggrey A et al.

Clin Exp Allergy

Asthma and eczema

2021-06-22

Eight novel susceptibility loci and putative causal variants in atopic dermatitis.

Tanaka N, Koido M et al.

J Allergy Clin Immunol

Atopic dermatitis

2021-06-02

Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories.

Gabryszewski SJ, Chang X et al.

J Allergy Clin Immunol

Allergic march (atopic dermatitis to allergic rhinitis)

2020-07-07