Active: Cannabis use Clear all

GWAS 2023-11-20

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.

Levey DF, Galimberti M et al.

Nat Genet

As recreational use of cannabis is being decriminalized in many places and medical use widely sancti...

Cannabis use disorder

38289

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-15

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making is a common, heritable endophenotype seen across many psychiatric disorders. I...

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2072

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-08

Identifying Genetic Loci and Phenomic Associations of Substance Use Traits: A Multi-trait Analysis of GWAS (MTAG) study.

Xu H, Toikumo S et al.

Addiction

Background and aims: Genome-wide association studies (GWAS) of opioid use disorder (OUD) and cannabi...

Opioid use disorder (MTAG)

74635

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-22

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.

Hatoum AS, Colbert SMC et al.

Nat Ment Health

Genetic liability to substance use disorders can be parsed into loci that confer general or substanc...

Addiction risk factors

647703

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-25

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.

Deak JD, Zhou H et al.

Mol Psychiatry

Despite the large toll of opioid use disorder (OUD), genome-wide association studies (GWAS) of OUD t...

Opioid use disorder

554186

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-11

Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.

Yin B, Wang X et al.

Front Psychiatry

Coffee or caffeine consumption has been associated with neuropsychiatric disorders, implying a share...

Decaffeinated coffee consumption and/or alcohol use disorder score

451275

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-20

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

Johnson EC, Demontis D et al.

Lancet Psychiatry

Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and f...

Cannabis use disorder

384032

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-18

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans.

Cheng Z, Phokaew C et al.

Transl Psychiatry

Cannabis, the most widely used illicit drug, can induce hallucinations. Our understanding of the bio...

Hallucinations in long-term cannabis use

Replicated

7915

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-17

Genome-wide association study implicates CHRNA2 in cannabis use disorder.

Demontis D, Rajagopal VM et al.

Nat Neurosci

Cannabis is the most frequently used illicit psychoactive substance worldwide; around one in ten use...

Mental disorder

Replicated

51372

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-04

Genome-wide association studies of impulsive personality traits (BIS-11 and UPPSP) and drug experimentation in up to 22,861 adult research participants identify loci in the CACNA1I and CADM2 genes.

Sanchez-Roige S, Fontanillas P et al.

J Neurosci

Impulsive personality traits are complex heritable traits that are governed by frontal-subcortical c...

Sensation seeking

22745

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-04

Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.

Soler Artigas M, Sánchez-Mora C et al.

Mol Psychiatry

Attention-deficit/hyperactivity disorder (ADHD) is a severely impairing neurodevelopmental disorder ...

Attention deficit hyperactivity disorder or cannabis use

83129

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-27

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

Pasman JA, Verweij KJH et al.

Nat Neurosci

Cannabis use is a heritable trait that has been associated with adverse mental health outcomes. In t...

Cannabis use

184756

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.

Levey DF, Galimberti M et al.

Nat Genet

Cannabis use disorder

2023-11-20

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2023-08-15

Identifying Genetic Loci and Phenomic Associations of Substance Use Traits: A Multi-trait Analysis of GWAS (MTAG) study.

Xu H, Toikumo S et al.

Addiction

Opioid use disorder (MTAG)

2023-05-08

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.

Hatoum AS, Colbert SMC et al.

Nat Ment Health

Addiction risk factors

2023-03-22

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.

Deak JD, Zhou H et al.

Mol Psychiatry

Opioid use disorder

2022-07-25

Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.

Yin B, Wang X et al.

Front Psychiatry

Decaffeinated coffee consumption and/or alcohol use disorder score

2022-07-11

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

Johnson EC, Demontis D et al.

Lancet Psychiatry

Cannabis use disorder

2020-10-20

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans.

Cheng Z, Phokaew C et al.

Transl Psychiatry

Hallucinations in long-term cannabis use

2019-11-18

Genome-wide association study implicates CHRNA2 in cannabis use disorder.

Demontis D, Rajagopal VM et al.

Nat Neurosci

Mental disorder

2019-06-17

Genome-wide association studies of impulsive personality traits (BIS-11 and UPPSP) and drug experimentation in up to 22,861 adult research participants identify loci in the CACNA1I and CADM2 genes.

Sanchez-Roige S, Fontanillas P et al.

J Neurosci

Sensation seeking

2019-02-04

Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.

Soler Artigas M, Sánchez-Mora C et al.

Mol Psychiatry

Attention deficit hyperactivity disorder or cannabis use

2019-01-04

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

Pasman JA, Verweij KJH et al.

Nat Neurosci

Cannabis use

2018-08-27