Active: Cognitive function Clear all

GWAS 2025-03-01

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Proteins encoded by exons are critical for cellular functions, and mutations in these genes often re...

Superior cerebellar peduncle fractional anisotropy

35412

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-18

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Approximately 40% of dementia cases could be prevented or delayed by modifiable risk factors related...

Global cortical thickness (GlobalMeanMean)

34552

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-04

Genetic architecture of the structural connectome.

Wainberg M, Forde NJ et al.

Nat Commun

Myelinated axons form long-range connections that enable rapid communication between distant brain r...

Left-hemisphere control network to right-hemisphere salience/ventral attention network white-matter structural connectivity

Replicated

26998

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-18

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Identifying the clinical implications and modifiable and unmodifiable factors of aging requires the ...

Biological age gap

9008

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-26

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy.

Hindley G, Shadrin AA et al.

Nat Hum Behav

Personality and cognitive function are heritable mental traits whose genetic foundations may be dist...

Personality traits or cognitive traits (multivariate analysis)

337125

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-27

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community.

Soo CC, Brandenburg JT et al.

Commun Biol

Cognitive function is an indicator for global physical and mental health, and cognitive impairment h...

Executive function

1887

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-06

The genetic architectures of functional and structural connectivity properties within cerebral resting-state networks.

Tissink E, Werme J et al.

eNeuro

Functional connectivity within resting-state networks (RSN-FC) is vital for cognitive functioning. R...

Functional connectivity (default mode network)

Replicated

27744

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-09

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.

Rajagopal VM, Ganna A et al.

Sci Rep

Cognitive functions of individuals with psychiatric disorders differ from that of the general popula...

School performance E-factor 1 (overall performance)

30982

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-29

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Complex traits show clear patterns of tissue-specific expression influenced by single nucleotide pol...

Inflammatory bowel disease

335453

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-16

Genome-wide association study of cerebellar volume provides insights into heritable mechanisms underlying brain development and mental health.

Tissink E, de Lange SC et al.

Commun Biol

Cerebellar volume is highly heritable and associated with neurodevelopmental and neurodegenerative d...

Total cerebellar volume

Replicated

31392

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-14

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Deficits in executive functions (EFs), cognitive processes that control goal-directed behaviors, are...

Common executive function

427037

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-05

Genetic variants associated with longitudinal changes in brain structure across the lifespan.

Brouwer RM, Klein M et al.

Nat Neurosci

Human brain structure changes throughout the lifespan. Altered brain growth or rates of decline are ...

Amygdala volume change rate

15100

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Superior cerebellar peduncle fractional anisotropy

2025-03-01

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Global cortical thickness (GlobalMeanMean)

2024-06-18

Genetic architecture of the structural connectome.

Wainberg M, Forde NJ et al.

Nat Commun

Left-hemisphere control network to right-hemisphere salience/ventral attention network white-matter structural connectivity

2024-03-04

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Biological age gap

2023-09-18

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy.

Hindley G, Shadrin AA et al.

Nat Hum Behav

Personality traits or cognitive traits (multivariate analysis)

2023-06-26

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community.

Soo CC, Brandenburg JT et al.

Commun Biol

Executive function

2023-03-27

The genetic architectures of functional and structural connectivity properties within cerebral resting-state networks.

Tissink E, Werme J et al.

eNeuro

Functional connectivity (default mode network)

2023-03-06

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.

Rajagopal VM, Ganna A et al.

Sci Rep

School performance E-factor 1 (overall performance)

2023-01-09

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Inflammatory bowel disease

2022-11-29

Genome-wide association study of cerebellar volume provides insights into heritable mechanisms underlying brain development and mental health.

Tissink E, de Lange SC et al.

Commun Biol

Total cerebellar volume

2022-07-16

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Common executive function

2022-07-14

Genetic variants associated with longitudinal changes in brain structure across the lifespan.

Brouwer RM, Klein M et al.

Nat Neurosci

Amygdala volume change rate

2022-04-05