Active: Corneal astigmatism Clear all

GWAS 2018-10-10

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.

Shah RL, Guggenheim JA

Hum Genet

Previous studies have suggested that naturally occurring genetic variation contributes to the risk o...

Corneal astigmatism

86335

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-05

A genome-wide association study of corneal astigmatism: The CREAM Consortium.

Shah RL, Li Q et al.

Mol Vis

Purpose: To identify genes and genetic markers associated with corneal astigmatism.

Corneal astigmatism

31370

Participants

N/A

Studies

Details PubMed

GWAS 2013-06-06

Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

Yazar S, Mishra A et al.

Mol Vis

Purpose: Corneal astigmatism is a common eye disorder characterized by irregularities in corneal cur...

Corneal astigmatism

2784

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-15

Identification of a candidate gene for astigmatism.

Lopes MC, Hysi PG et al.

Invest Ophthalmol Vis Sci

Purpose: Astigmatism is a common refractive error that reduces vision, where the curvature and refra...

Corneal astigmatism

22100

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-03

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α gene as a quantitative trait locus for eye size in white Europeans.

Guggenheim JA, McMahon G et al.

Mol Vis

Purpose: Corneal curvature is a key determinant of the refractive power of the eye. Variants in two ...

Corneal curvature

Replicated

9383

Participants

N/A

Studies

Details PubMed

GWAS 2011-12-01

Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.

Fan Q, Zhou X et al.

PLoS Genet

Corneal astigmatism refers to refractive abnormalities and irregularities in the curvature of the co...

Corneal astigmatism

Replicated

8513

Participants

N/A

Studies

Details PubMed

GWAS 2011-06-10

Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.

Han S, Chen P et al.

Hum Mol Genet

Corneal curvature (CC) is a key determinant of major eye diseases, such as keratoconus, myopia and c...

Corneal curvature

Replicated

7360

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.

Shah RL, Guggenheim JA

Hum Genet

Corneal astigmatism

2018-10-10

A genome-wide association study of corneal astigmatism: The CREAM Consortium.

Shah RL, Li Q et al.

Mol Vis

Corneal astigmatism

2018-02-05

Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

Yazar S, Mishra A et al.

Mol Vis

Corneal astigmatism

2013-06-06

Identification of a candidate gene for astigmatism.

Lopes MC, Hysi PG et al.

Invest Ophthalmol Vis Sci

Corneal astigmatism

2013-01-15

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α gene as a quantitative trait locus for eye size in white Europeans.

Guggenheim JA, McMahon G et al.

Mol Vis

Corneal curvature

2013-01-03

Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.

Fan Q, Zhou X et al.

PLoS Genet

Corneal astigmatism

2011-12-01

Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.

Han S, Chen P et al.

Hum Mol Genet

Corneal curvature

2011-06-10