Active: Eye color Clear all

GWAS 2021-03-10

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color.

Simcoe M, Valdes A et al.

Sci Adv

Human eye color is highly heritable, but its genetic architecture is not yet fully understood. We re...

Eye color

Replicated

194622

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-02

Chances and challenges of machine learning-based disease classification in genetic association studies illustrated on age-related macular degeneration.

Guenther F, Brandl C et al.

Genet Epidemiol

Imaging technology and machine learning algorithms for disease classification set the stage for high...

Age-related macular degeneration

48065

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-11

Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1.

Thomsen H, Chattopadhyay S et al.

Melanoma Res

Uveal melanoma is a life-threatening disease for which data on germline predisposition are essential...

Uveal melanoma

5789

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-01

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

Zhang M, Song F et al.

Hum Mol Genet

Aiming to identify novel genetic loci for pigmentation and skin cancer, we conducted a series of gen...

Sunburns

Replicated

13519

Participants

N/A

Studies

Details PubMed

GWAS 2012-10-31

Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.

Candille SI, Absher DM et al.

PLoS One

Pigmentation of the skin, hair, and eyes varies both within and between human populations. Identifyi...

Eye color

Replicated

468

Participants

N/A

Studies

Details PubMed

GWAS 2011-09-22

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.

Amos CI, Wang LE et al.

Hum Mol Genet

We performed a multistage genome-wide association study of melanoma. In a discovery cohort of 1804 m...

Melanoma

Replicated

32637

Participants

N/A

Studies

Details PubMed

GWAS 2010-06-24

Web-based, participant-driven studies yield novel genetic associations for common traits.

Eriksson N, Macpherson JM et al.

PLoS Genet

Despite the recent rapid growth in genome-wide data, much of human variation remains entirely unexpl...

Hair color

9126

Participants

N/A

Studies

Details PubMed

GWAS 2010-05-16

Digital quantification of human eye color highlights genetic association of three new loci.

Liu F, Wollstein A et al.

PLoS Genet

Previous studies have successfully identified genetic variants in several genes associated with huma...

Eye color traits

Replicated

9494

Participants

N/A

Studies

Details PubMed

GWAS 2008-05-16

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.

Han J, Kraft P et al.

PLoS Genet

We conducted a multi-stage genome-wide association study of natural hair color in more than 10,000 m...

Black vs. blond hair color

Replicated

10752

Participants

N/A

Studies

Details PubMed

GWAS 2008-01-24

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.

Kayser M, Liu F et al.

Am J Hum Genet

Human iris color was one of the first traits for which Mendelian segregation was established. To dat...

Iris color

Replicated

8273

Participants

N/A

Studies

Details PubMed

GWAS 2007-10-21

Genetic determinants of hair, eye and skin pigmentation in Europeans.

Sulem P, Gudbjartsson DF et al.

Nat Genet

Hair, skin and eye colors are highly heritable and visible traits in humans. We carried out a genome...

Skin sensitivity to sun

Replicated

6918

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color.

Simcoe M, Valdes A et al.

Sci Adv

Eye color

2021-03-10

Chances and challenges of machine learning-based disease classification in genetic association studies illustrated on age-related macular degeneration.

Guenther F, Brandl C et al.

Genet Epidemiol

Age-related macular degeneration

2020-08-02

Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1.

Thomsen H, Chattopadhyay S et al.

Melanoma Res

Uveal melanoma

2019-10-11

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

Zhang M, Song F et al.

Hum Mol Genet

Sunburns

2013-04-01

Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.

Candille SI, Absher DM et al.

PLoS One

Eye color

2012-10-31

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.

Amos CI, Wang LE et al.

Hum Mol Genet

Melanoma

2011-09-22

Web-based, participant-driven studies yield novel genetic associations for common traits.

Eriksson N, Macpherson JM et al.

PLoS Genet

Hair color

2010-06-24

Digital quantification of human eye color highlights genetic association of three new loci.

Liu F, Wollstein A et al.

PLoS Genet

Eye color traits

2010-05-16

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.

Han J, Kraft P et al.

PLoS Genet

Black vs. blond hair color

2008-05-16

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.

Kayser M, Liu F et al.

Am J Hum Genet

Iris color

2008-01-24

Genetic determinants of hair, eye and skin pigmentation in Europeans.

Sulem P, Gudbjartsson DF et al.

Nat Genet

Skin sensitivity to sun

2007-10-21