Active: Headache Clear all

GWAS 2023-10-16

Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.

Mocci E, Ward K et al.

PLoS Genet

Chronic pain is at epidemic proportions in the United States, represents a significant burden on our...

Pain (pleiotropy)

361194

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-19

Genome-wide association studies of response and side effects to the BNT162b2 vaccine in Italian healthcare workers: Increased antibody levels and side effects in carriers of the HLA-A*03:01 allele.

Magri C, Marchina E et al.

HLA

The remarkable variability of response to vaccines against SARS-CoV-2 is apparent. The present study...

Response to BNT162b2 vaccine (anti-SARS-CoV-2 Spike antibody levels at two months after first dose)

873

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-24

Genome-phenome wide association study of broadly defined headache.

Hsu WT, Lee YT et al.

Brain Commun

Until recently, most genetic studies of headache have been conducted on participants with European a...

Headache

108855

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-26

Genetic analysis of probable sleep bruxism and its associations with clinical and behavioral traits.

Strausz T, Strausz S et al.

Sleep

Study objectives: Sleep bruxism (SB) can cause damage on teeth, headache and severe pain affecting b...

Probable sleep bruxism

377277

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-20

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

The co-occurrence of migraine and glycemic traits has long been reported in observational epidemiolo...

Migraine or 2-hr glucose levels

937810

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-18

A Meta-Analysis of the Genome-Wide Association Studies on Two Genetically Correlated Phenotypes Suggests Four New Risk Loci for Headaches.

Meng W, Reel PS et al.

Phenomics

Headache is one of the commonest complaints that doctors need to address in clinical settings. The g...

Headache or migraine

397385

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-12

Genetic Overlap Analysis Identifies a Shared Etiology between Migraine and Headache with Type 2 Diabetes.

Islam MR, The International Headache Genetics Consortium Ihgc None et al.

Genes (Basel)

Migraine and headache frequently co-occur with type 2 diabetes (T2D), suggesting a shared aetiology ...

Migraine or type 2 diabetes

1771471

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-18

Genome-wide association study reveals susceptibility loci for self-reported headache in a large community-based Asian population.

Tsao YC, Wang SJ et al.

Cephalalgia

The genetic substrate for headache in the general population has not been identified in Asians. We i...

Headache

13906

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-22

New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis.

Choquet H, Yin J et al.

Commun Biol

Migraine is a common disabling primary headache disorder that is ranked as the most common neurologi...

Migraine

554569

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-29

Genome Wide Association Study Identifies Risk Loci For Cluster Headache.

O'Connor E, Fourier C et al.

Ann Neurol

Objective: This study was undertaken to identify susceptibility loci for cluster headache and obtain...

Cluster headache

8191

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-31

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).

Meng W, Adams MJ et al.

EBioMedicine

Headache is the most common neurological symptom and a leading cause of years lived with disability....

Headache

223782

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-13

A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants.

Bacchelli E, Cainazzo MM et al.

J Headache Pain

Cluster Headache (CH) is a severe primary headache, with a poorly understood pathophysiology. Comple...

Cluster headache

458

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.

Mocci E, Ward K et al.

PLoS Genet

Pain (pleiotropy)

2023-10-16

Genome-wide association studies of response and side effects to the BNT162b2 vaccine in Italian healthcare workers: Increased antibody levels and side effects in carriers of the HLA-A*03:01 allele.

Magri C, Marchina E et al.

HLA

Response to BNT162b2 vaccine (anti-SARS-CoV-2 Spike antibody levels at two months after first dose)

2023-07-19

Genome-phenome wide association study of broadly defined headache.

Hsu WT, Lee YT et al.

Brain Commun

Headache

2023-05-24

Genetic analysis of probable sleep bruxism and its associations with clinical and behavioral traits.

Strausz T, Strausz S et al.

Sleep

Probable sleep bruxism

2023-04-26

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

Migraine or 2-hr glucose levels

2023-02-20

A Meta-Analysis of the Genome-Wide Association Studies on Two Genetically Correlated Phenotypes Suggests Four New Risk Loci for Headaches.

Meng W, Reel PS et al.

Phenomics

Headache or migraine

2022-11-18

Genetic Overlap Analysis Identifies a Shared Etiology between Migraine and Headache with Type 2 Diabetes.

Islam MR, The International Headache Genetics Consortium Ihgc None et al.

Genes (Basel)

Migraine or type 2 diabetes

2022-10-12

Genome-wide association study reveals susceptibility loci for self-reported headache in a large community-based Asian population.

Tsao YC, Wang SJ et al.

Cephalalgia

Headache

2021-08-18

New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis.

Choquet H, Yin J et al.

Commun Biol

Migraine

2021-07-22

Genome Wide Association Study Identifies Risk Loci For Cluster Headache.

O'Connor E, Fourier C et al.

Ann Neurol

Cluster headache

2021-06-29

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).

Meng W, Adams MJ et al.

EBioMedicine

Headache

2018-01-31

A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants.

Bacchelli E, Cainazzo MM et al.

J Headache Pain

Cluster headache

2016-12-13