Active: Irritable bowel syndrome Clear all

GWAS 2024-11-23

Shared genetic architecture and causality between autism spectrum disorder and irritable bowel syndrome, multisite pain, and fatigue.

Li Y, Xie T et al.

Transl Psychiatry

Autism spectrum disorder (ASD) often co-occurs with functional somatic syndromes (FSS), such as irri...

Autism spectrum disorder (MTAG)

46350

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-15

Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.

Liu X, Li D et al.

Front Immunol

It has been reported that COVID-19 patients have an increased risk of developing IBS; however, the u...

Irritable bowel syndrome or COVID-19 susceptibility / hospitalization (MTAG)

5519491

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-18

Rome III criteria capture higher irritable bowel syndrome SNP-heritability and highlight a novel genetic link with cardiovascular traits.

Camargo Tavares L, Lopera-Maya EA et al.

Cell Mol Gastroenterol Hepatol

Background & aims: Irritable bowel syndrome (IBS) shows genetic predisposition, and large-scale ...

Irritable bowel syndrome

101884

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-05

150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.

Wu Y, Goleva SB et al.

Cell Genom

We conducted a genome-wide association study (GWAS) analysis of diverticular disease (DivD) of intes...

Diverticular disease

454768

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-21

Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.

Alemany S, Soler-Artigas M et al.

J Transl Med

Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction frequently accompanied...

Irritable bowel syndrome (MTAG)

887490

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-31

The Causal Association of Irritable Bowel Syndrome with Multiple Disease Outcomes: A Phenome-Wide Mendelian Randomization Study.

Li C, Chen Y et al.

J Clin Med

This study aimed to identify novel associations between irritable bowel syndrome (IBS) and a broad r...

Irritable bowel syndrome

173176

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-18

A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders.

Adewuyi EO, O'Brien EK et al.

Commun Biol

Consistent with the concept of the gut-brain phenomenon, observational studies suggest a relationshi...

Alzheimer's disease or gastroesophageal reflux disease

787859

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-23

Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome.

Vollert J, Wang R et al.

Front Psychiatry

Irritable bowel syndrome (IBS) is a highly prevalent chronic pain disorder with multiple underlying ...

Response to treatment in irritable bowel syndrome (pain frequency)

212

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-04

Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome.

Wang RS, Lembo AJ et al.

Front Pain Res (Lausanne)

Background and Aims: Irritable bowel syndrome (IBS), a functional pain disorder of gut-brain interac...

Response to treatment in irritable bowel syndrome (symptom severity)

188

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-08

GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome.

Bonfiglio F, Liu X et al.

Cell Genom

Gut dysmotility is associated with constipation, diarrhea, and functional gastrointestinal disorders...

Stool frequency

167875

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-05

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Eijsbouts C, Zheng T et al.

Nat Genet

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptib...

Irritable bowel syndrome

Replicated

2075908

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-19

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression.

Wu Y, Murray GK et al.

Nat Commun

Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other gastrointestina...

Peptic ulcer disease

456327

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Shared genetic architecture and causality between autism spectrum disorder and irritable bowel syndrome, multisite pain, and fatigue.

Li Y, Xie T et al.

Transl Psychiatry

Autism spectrum disorder (MTAG)

2024-11-23

Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.

Liu X, Li D et al.

Front Immunol

Irritable bowel syndrome or COVID-19 susceptibility / hospitalization (MTAG)

2024-11-15

Rome III criteria capture higher irritable bowel syndrome SNP-heritability and highlight a novel genetic link with cardiovascular traits.

Camargo Tavares L, Lopera-Maya EA et al.

Cell Mol Gastroenterol Hepatol

Irritable bowel syndrome

2024-04-18

150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.

Wu Y, Goleva SB et al.

Cell Genom

Diverticular disease

2023-06-05

Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.

Alemany S, Soler-Artigas M et al.

J Transl Med

Irritable bowel syndrome (MTAG)

2023-04-21

The Causal Association of Irritable Bowel Syndrome with Multiple Disease Outcomes: A Phenome-Wide Mendelian Randomization Study.

Li C, Chen Y et al.

J Clin Med

Irritable bowel syndrome

2023-01-31

A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders.

Adewuyi EO, O'Brien EK et al.

Commun Biol

Alzheimer's disease or gastroesophageal reflux disease

2022-07-18

Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome.

Vollert J, Wang R et al.

Front Psychiatry

Response to treatment in irritable bowel syndrome (pain frequency)

2022-03-23

Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome.

Wang RS, Lembo AJ et al.

Front Pain Res (Lausanne)

Response to treatment in irritable bowel syndrome (symptom severity)

2022-01-04

GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome.

Bonfiglio F, Liu X et al.

Cell Genom

Stool frequency

2021-12-08

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Eijsbouts C, Zheng T et al.

Nat Genet

Irritable bowel syndrome

2021-11-05

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression.

Wu Y, Murray GK et al.

Nat Commun

Peptic ulcer disease

2021-02-19