Active: Ischemic stroke Clear all

GWAS 2025-06-13

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Brain geometry affects brain function. A quantitative encoding of form is provided by the Laplace-Be...

Left accumbens area shape (Laplace-Beltrami spectrum)

Replicated

24823

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-17

Genome-wide and phenome-wide studies provided insights into brain glymphatic system function and its clinical associations.

Ran L, Fang Y et al.

Sci Adv

We applied an MRI technique diffusion tensor imaging along the perivascular space (DTI-ALPS) for ass...

Anterior diffusion tensor imaging along the perivascular space index

31629

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-02

Evidence of survival bias in the association between <i>APOE-Є4</i> and age at ischemic stroke onset.

von Berg J, McArdle PF et al.

Front Genet

Introduction: Large genome-wide association studies (GWASs) using case-control study designs have no...

Age of onset of ischemic stroke

Replicated

22396

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-05

Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.

Akinyemi RO, Tiwari HK et al.

Genome Med

African ancestry populations have the highest burden of stroke worldwide, yet the genetic basis of s...

Ischemic stroke

3421

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-30

Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes.

Llucià-Carol L, Muiño E et al.

Int J Mol Sci

We aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after th...

Ischemic stroke after COVID-19

774

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-21

The STROMICS genome study: deep whole-genome sequencing and analysis of 10K Chinese patients with ischemic stroke reveal complex genetic and phenotypic interplay.

Cheng S, Xu Z et al.

Cell Discov

Ischemic stroke is a leading cause of global mortality and long-term disability. However, there is a...

Apolipoprotein A-I levels

10241

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-19

Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries.

Surakka I, Wu KH et al.

Cell Genom

Stroke is the second leading cause of death and disability worldwide. Stroke prevalence varies by se...

Ischemic stroke

Replicated

2484809

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-10

Whole-Exome Sequencing Analyses Support a Role of Vitamin D Metabolism in Ischemic Stroke.

Xie Y, Acosta JN et al.

Stroke

Ischemic stroke (IS) is a highly heritable trait, and genome-wide association studies have identifie...

Ischemic stroke

152058

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-24

Exome Array Analysis of 9721 Ischemic Stroke Cases from the SiGN Consortium.

Xu H, Nguyen K et al.

Genes (Basel)

Recent genome wide association studies have identified 89 common genetic variants robustly associate...

Ischemic stroke

Replicated

145382

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-14

Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events.

Attelind S, Hallberg P et al.

Front Genet

Apixaban is a direct oral anticoagulant, a factor Xa inhibitor, used for the prevention of ischemic ...

Cmax at steady-state of apixaban

1325

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-31

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke.

Jaworek T, Xu H et al.

Neurology

Background and objectives: Current genome-wide association studies of ischemic stroke have focused p...

Early-onset ischemic stroke

615660

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-14

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study.

Dofuku S, Sonehara K et al.

Transl Stroke Res

The genetic background of intracranial artery stenosis (ICAS), a major cause of ischemic stroke, rem...

Intracranial artery stenosis

715

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Left accumbens area shape (Laplace-Beltrami spectrum)

2025-06-13

Genome-wide and phenome-wide studies provided insights into brain glymphatic system function and its clinical associations.

Ran L, Fang Y et al.

Sci Adv

Anterior diffusion tensor imaging along the perivascular space index

2025-01-17

Evidence of survival bias in the association between <i>APOE-Є4</i> and age at ischemic stroke onset.

von Berg J, McArdle PF et al.

Front Genet

Age of onset of ischemic stroke

2024-09-02

Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.

Akinyemi RO, Tiwari HK et al.

Genome Med

Ischemic stroke

2024-02-05

Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes.

Llucià-Carol L, Muiño E et al.

Int J Mol Sci

Ischemic stroke after COVID-19

2023-08-30

The STROMICS genome study: deep whole-genome sequencing and analysis of 10K Chinese patients with ischemic stroke reveal complex genetic and phenotypic interplay.

Cheng S, Xu Z et al.

Cell Discov

Apolipoprotein A-I levels

2023-07-21

Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries.

Surakka I, Wu KH et al.

Cell Genom

Ischemic stroke

2023-06-19

Whole-Exome Sequencing Analyses Support a Role of Vitamin D Metabolism in Ischemic Stroke.

Xie Y, Acosta JN et al.

Stroke

Ischemic stroke

2023-02-10

Exome Array Analysis of 9721 Ischemic Stroke Cases from the SiGN Consortium.

Xu H, Nguyen K et al.

Genes (Basel)

Ischemic stroke

2022-12-24

Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events.

Attelind S, Hallberg P et al.

Front Genet

Cmax at steady-state of apixaban

2022-09-14

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke.

Jaworek T, Xu H et al.

Neurology

Early-onset ischemic stroke

2022-08-31

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study.

Dofuku S, Sonehara K et al.

Transl Stroke Res

Intracranial artery stenosis

2022-06-14