Active: Pancreatic cancer Clear all

GWAS 2025-03-07

The contribution of coding variants to the heritability of multiple cancer types using UK Biobank whole-exome sequencing data.

Wilcox N, Tyrer JP et al.

Am J Hum Genet

Genome-wide association studies have been highly successful at identifying common variants associate...

Pancreatic cancer (Gene-based burden)

419307

Participants

N/A

Studies

Details PubMed

GWAS 2024-12-05

A genome-wide association study identifies eight loci associated with intraductal papillary mucinous neoplasm progression toward malignancy.

Gentiluomo M, Corradi C et al.

Cancer

Intraductal papillary mucinous neoplasms (IPMNs) are precursors to pancreatic cancer, but not all IP...

Intraductal papillary mucinous neoplasm (adjusted for cyst)

338

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-13

Genome-wide analysis to assess if heavy alcohol consumption modifies the association between SNPs and pancreatic cancer risk.

Ni Z, Kundu P et al.

Cancer Epidemiol Biomarkers Prev

Pancreatic cancer is a leading cause of cancer-related death globally. Risk factors for pancreatic c...

Pancreatic cancer x heavy alcohol consumption interaction (1df)

10134

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-14

Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).

Quintanilha JCF, Sibley AB et al.

BMC Genomics

Herein, we report results from a genome-wide study conducted to identify protein quantitative trait ...

Angiopoietin-2 levels in metastatic colorectal cancer

869

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-01

Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking.

Zhu H, Choi J et al.

JCO Precis Oncol

Purpose: Pancreatic cancer (PC) is a deadly disease most often diagnosed in late stages. Identificat...

Pancreatic cancer x smoking interaction

315512

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-25

Genetic and non-genetic risk factors for early-onset pancreatic cancer.

Nodari Y, Gentiluomo M et al.

Dig Liver Dis

Early-onset pancreatic cancer (EOPC) represents 5-10% of all pancreatic ductal adenocarcinoma (PDAC)...

Early-onset pancreatic cancer

Replicated

11134

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-03

Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk.

Lu Y, Gentiluomo M et al.

Front Oncol

Although 21 pancreatic cancer susceptibility loci have been identified in individuals of European an...

Pancreatic cancer

Replicated

22826

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-03

Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.

Pistoni L, Gentiluomo M et al.

Carcinogenesis

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Its poor prognosis is pred...

Pancreatic ductal adenocarcinoma

Replicated

57497

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-01

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer.

López de Maturana E, Rodríguez JA et al.

Genome Med

Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay....

Pancreatic cancer

Replicated

2017

Participants

N/A

Studies

Details PubMed

GWAS 2020-07-15

A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population.

Streicher SA, Klein AP et al.

Hum Genet

Jews are estimated to be at increased risk of pancreatic cancer compared to non-Jews, but their obse...

Pancreatic cancer

2738

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-24

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.

Lin Y, Nakatochi M et al.

Nat Commun

Pancreatic cancer is the fourth leading cause of cancer-related deaths in Japan. To identify risk lo...

Pancreatic cancer

Replicated

45453

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-09

Genome-wide association study identifies an early onset pancreatic cancer risk locus.

Campa D, Gentiluomo M et al.

Int J Cancer

Early onset pancreatic cancer (EOPC) is a rare disease with a very high mortality rate. Almost nothi...

Pancreatic ductal adenocarcinoma (age of onset)(over 60 vs under 60)

Replicated

13259

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The contribution of coding variants to the heritability of multiple cancer types using UK Biobank whole-exome sequencing data.

Wilcox N, Tyrer JP et al.

Am J Hum Genet

Pancreatic cancer (Gene-based burden)

2025-03-07

A genome-wide association study identifies eight loci associated with intraductal papillary mucinous neoplasm progression toward malignancy.

Gentiluomo M, Corradi C et al.

Cancer

Intraductal papillary mucinous neoplasm (adjusted for cyst)

2024-12-05

Genome-wide analysis to assess if heavy alcohol consumption modifies the association between SNPs and pancreatic cancer risk.

Ni Z, Kundu P et al.

Cancer Epidemiol Biomarkers Prev

Pancreatic cancer x heavy alcohol consumption interaction (1df)

2024-06-13

Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).

Quintanilha JCF, Sibley AB et al.

BMC Genomics

Angiopoietin-2 levels in metastatic colorectal cancer

2024-05-14

Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking.

Zhu H, Choi J et al.

JCO Precis Oncol

Pancreatic cancer x smoking interaction

2024-03-01

Genetic and non-genetic risk factors for early-onset pancreatic cancer.

Nodari Y, Gentiluomo M et al.

Dig Liver Dis

Early-onset pancreatic cancer

2023-03-25

Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk.

Lu Y, Gentiluomo M et al.

Front Oncol

Pancreatic cancer

2021-12-03

Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.

Pistoni L, Gentiluomo M et al.

Carcinogenesis

Pancreatic ductal adenocarcinoma

2021-07-03

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer.

López de Maturana E, Rodríguez JA et al.

Genome Med

Pancreatic cancer

2021-02-01

A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population.

Streicher SA, Klein AP et al.

Hum Genet

Pancreatic cancer

2020-07-15

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.

Lin Y, Nakatochi M et al.

Nat Commun

Pancreatic cancer

2020-06-24

Genome-wide association study identifies an early onset pancreatic cancer risk locus.

Campa D, Gentiluomo M et al.

Int J Cancer

Pancreatic ductal adenocarcinoma (age of onset)(over 60 vs under 60)

2020-04-09