Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.
Sobrin L, Ripke S, Yu Y et al.
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Abstract
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Purpose: To investigate whether the 2 subtypes of advanced age-related macular degeneration (AMD), choroidal neovascularization (CNV), and geographic atrophy (GA) segregate separately in families and to identify which genetic variants are associated with these 2 subtypes.
1,775 European ancestry choroidal neovascularization cases, 4,134 European ancestry controls
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