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GWAS Study

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.

Stanescu HC, Arcos-Burgos M, Medlar A et al.

21323541 PubMed ID
GWAS Study Type
2894 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SH
Stanescu HC
AM
Arcos-Burgos M
MA
Medlar A
BD
Bockenhauer D
KA
Kottgen A
DL
Dragomirescu L
VC
Voinescu C
PN
Patel N
PK
Pearce K
HM
Hubank M
SH
Stephens HA
LV
Laundy V
PS
Padmanabhan S
ZA
Zawadzka A
HJ
Hofstra JM
CM
Coenen MJ
DH
den Heijer M
KL
Kiemeney LA
BD
Bacq-Daian D
SB
Stengel B
PS
Powis SH
BP
Brenchley P
FJ
Feehally J
RA
Rees AJ
DH
Debiec H
WJ
Wetzels JF
RP
Ronco P
MP
Mathieson PW
KR
Kleta R
Chapter II

Abstract

Summary of the research findings

Idiopathic membranous nephropathy is a major cause of the nephrotic syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic basis of biopsy-proven cases of idiopathic membranous nephropathy in a white population.

556 European ancestry cases, 2,338 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2894
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Netherlands, U.K., France
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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