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GWAS Study

Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm.

Zheng HF, Duncan EL, Yerges-Armstrong LM et al.

23572186 PubMed ID
GWAS Study Type
6581 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZH
Zheng HF
DE
Duncan EL
YL
Yerges-Armstrong LM
EJ
Eriksson J
BU
Bergström U
LP
Leo PJ
LW
Leslie WD
GD
Goltzman D
BJ
Blangero J
HD
Hanley DA
CM
Carless MA
SE
Streeten EA
LM
Lorentzon M
BM
Brown MA
ST
Spector TD
PU
Pettersson-Kymmer U
OC
Ohlsson C
MB
Mitchell BD
RJ
Richards JB
Chapter II

Abstract

Summary of the research findings

Forearm fractures affect 1.7 million individuals worldwide each year and most occur earlier in life than hip fractures. While the heritability of forearm bone mineral density (BMD) and fracture is high, their genetic determinants are largely unknown.

5,866 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

6581
Total Participants
GWAS
Study Type
Yes
Replicated
715 Mexican American individuals
Replication Participants
European, Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.