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GWAS Study

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.

Germain M, Pezzolesi MG, Sandholm N et al.

25476525 PubMed ID
GWAS Study Type
7803 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GM
Germain M
PM
Pezzolesi MG
SN
Sandholm N
MA
McKnight AJ
SK
Susztak K
LM
Lajer M
FC
Forsblom C
MM
Marre M
PH
Parving HH
RP
Rossing P
TI
Toppila I
SJ
Skupien J
RR
Roussel R
KY
Ko YA
LN
Ledo N
FL
Folkersen L
CM
Civelek M
MA
Maxwell AP
TD
Tregouet DA
GP
Groop PH
TL
Tarnow L
HS
Hadjadj S
Chapter II

Abstract

Summary of the research findings

Aims/hypothesis: The genetic determinants of diabetic nephropathy remain poorly understood. We aimed to identify novel susceptibility genes for diabetic nephropathy.

683 European ancestry cases, 779 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

7803
Total Participants
GWAS
Study Type
Yes
Replicated
2,962 European ancestry cases, 3,379 European ancestry controls
Replication Participants
European
Ancestry
Finland, Belgium, France
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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