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GWAS Study

Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).

Saccone NL, Emery LS, Sofer T et al.

28520984 PubMed ID
GWAS Study Type
5804 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SN
Saccone NL
EL
Emery LS
ST
Sofer T
GS
Gogarten SM
BD
Becker DM
BE
Bottinger EP
CL
Chen LS
CR
Culverhouse RC
DW
Duan W
HD
Hancock DB
HH
Hosgood HD
JE
Johnson EO
LR
Loos RJF
LT
Louie T
PG
Papanicolaou G
PK
Perreira KM
RE
Rodriquez EJ
SC
Schurmann C
SA
Stilp AM
SA
Szpiro AA
TG
Talavera GA
TK
Taylor KD
TJ
Thrasher JF
YL
Yanek LR
LC
Laurie CC
PE
Pérez-Stable EJ
BL
Bierut LJ
KR
Kaplan RC
Chapter II

Abstract

Summary of the research findings

Introduction: Genetic variants associated with nicotine dependence have previously been identified, primarily in European-ancestry populations. No genome-wide association studies (GWAS) have been reported for smoking behaviors in Hispanics/Latinos in the United States and Latin America, who are of mixed ancestry with European, African, and American Indigenous components.

778 Hispanic non-daily smoker cases, 1,786 Hispanic daily smoker controls

Chapter III

Study Statistics

Key metrics and study information

5804
Total Participants
GWAS
Study Type
Yes
Replicated
85 Hispanic non-daily smokers, 343 Hispanic daily smokers, 158 African American non-daily smokers, 1,106 African American daily smokers, 232 European ancestry non-daily smokers, 1,316 European ancestry daily smokers
Replication Participants
Hispanic or Latin American, African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.