Common and rare variants genetic association analysis of cigarettes per day among ever smokers in COPD cases and controls.
Lutz SM, Frederiksen B, Begum F et al.
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Abstract
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Introduction: Cigarette smoking is a major environmental risk factor for many diseases, including chronic obstructive pulmonary disease (COPD). There are shared genetic influences on cigarette smoking and COPD. Genetic risk factors for cigarette smoking in cohorts enriched for COPD are largely unknown.
2,812 European ancestry cases, 3,846 European ancestry controls, 821 African American cases, 2,459 African American controls
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