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GWAS Study

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.

Lotta LA, Wittemans LBL, Zuber V et al.

30575882 PubMed ID
GWAS Study Type
660648 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LL
Lotta LA
WL
Wittemans LBL
ZV
Zuber V
SI
Stewart ID
SS
Sharp SJ
LJ
Luan J
DF
Day FR
LC
Li C
BN
Bowker N
CL
Cai L
DL
De Lucia Rolfe E
KK
Khaw KT
PJ
Perry JRB
OS
O'Rahilly S
SR
Scott RA
SD
Savage DB
BS
Burgess S
WN
Wareham NJ
LC
Langenberg C
Chapter II

Abstract

Summary of the research findings

Importance: Body fat distribution, usually measured using waist-to-hip ratio (WHR), is an important contributor to cardiometabolic disease independent of body mass index (BMI). Whether mechanisms that increase WHR via lower gluteofemoral (hip) or via higher abdominal (waist) fat distribution affect cardiometabolic risk is unknown.

660,648 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

660648
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.