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GWAS Study

A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity.

Zhu Z, Li J, Si J et al.

33766948 PubMed ID
GWAS Study Type
100285 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZZ
Zhu Z
LJ
Li J
SJ
Si J
MB
Ma B
SH
Shi H
LJ
Lv J
CW
Cao W
GY
Guo Y
MI
Millwood IY
WR
Walters RG
LK
Lin K
YL
Yang L
CY
Chen Y
DH
Du H
YB
Yu B
HK
Hasegawa K
CC
Camargo CA
MM
Moffatt MF
CW
Cookson WOC
CJ
Chen J
CZ
Chen Z
LL
Li L
YC
Yu C
LL
Liang L
Chapter II

Abstract

Summary of the research findings

Lung function is a heritable complex phenotype with obesity being one of its important risk factors. However, knowledge of their shared genetic basis is limited. Most genome-wide association studies (GWASs) for lung function have been based on European populations, limiting the generalisability across populations. Large-scale lung function GWASs in other populations are lacking.

100,285 Chinese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

100285
Total Participants
GWAS
Study Type
Yes
Replicated
up to 457,756 European ancestry individuals
Replication Participants
East Asian, European
Ancestry
China, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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