Evidence that the pituitary gland connects type 2 diabetes mellitus and schizophrenia based on large-scale trans-ethnic genetic analyses.
Cai L, Sun Y, Liu Y et al.
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Abstract
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Previous studies on European (EUR) samples have obtained inconsistent results regarding the genetic correlation between type 2 diabetes mellitus (T2DM) and Schizophrenia (SCZ). A large-scale trans-ethnic genetic analysis may provide additional evidence with enhanced power.
77,418 East Asian ancestry type 2 diabetes cases, 22,778 East Asian ancestry schizophrenia cases, 391,484 East Asian ancestry controls, 74,124 European ancestry type 2 diabetes cases, 33,640 European ancestry schizophrenia cases, 867,462 European ancestry controls
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