Health & Traits Publications

Rajabli F, Benchek P et al.

Genome Biol

Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in ances...

Alzheimer's disease

Ray NR, Kunkle BW et al.

Alzheimers Dement

Introduction: Despite a two-fold risk, individuals of African ancestry have been underrepresented in...

Late-onset Alzheimer's disease

Xicota L, Cosentino S et al.

Alzheimers Dement

Introduction: Late-onset Alzheimer's disease (LOAD) has a strong genetic component. Participants in ...

Late-onset Alzheimer's disease

Shigemizu D, Akiyama S et al.

Transl Psychiatry

Late-onset Alzheimer's disease (LOAD) is the most common multifactorial neurodegenerative disease am...

Late-onset Alzheimer's disease

Hou J, Hess JL et al.

Transl Psychiatry

Polygenic risk scores (PRSs) can boost risk prediction in late-onset Alzheimer's disease (LOAD) beyo...

Late-onset Alzheimer's disease in high risk polygenic risk score

Wightman DP, Jansen IE et al.

Nat Genet

Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts for 50-70%...

Late-onset Alzheimer's disease

Horimoto ARVR, Xue D et al.

Alzheimers Res Ther

Genetic studies have primarily been conducted in European ancestry populations, identifying dozens o...

Alzheimer's disease

Kang S, Gim J et al.

J Alzheimers Dis

The present study reports two novel genome-wide significant loci for late-onset Alzheimer's disease ...

Late-onset Alzheimer's disease

Lutz MW, Luo S et al.

Alzheimers Dement

Introduction: Late-onset Alzheimer's disease (LOAD) manifests comorbid neuropsychiatric symptoms and...

Alzheimer's disease or posttraumatic stress syndrome (pleiotropy)

Lutz MW, Sprague D et al.

Transl Psychiatry

Patients with late-onset Alzheimer's disease (LOAD) frequently manifest comorbid neuropsychiatric sy...

Late-onset Alzheimer's disease or major depressive disorder (pleiotropy)

Kunkle BW, Grenier-Boley B et al.

Nat Genet

Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by ...

Alzheimer's disease (late onset)

Mukherjee S, Mez J et al.

Mol Psychiatry

Categorizing people with late-onset Alzheimer's disease into biologically coherent subgroups is impo...

Alzheimer's disease with memory domain impairment