Active: Obstructive sleep apnea Clear all

GWAS 2025-06-04

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.

Kurniansyah N, Strausz SJ et al.

EBioMedicine

Obstructive sleep apnoea (OSA) is a common chronic condition, with obesity its strongest risk factor...

Obstructive sleep apnea

182017

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-27

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Sofer T, Kurniansyah N et al.

EBioMedicine

Genome-wide association studies (GWAS) for obstructive sleep apnoea (OSA) are limited due to the und...

Obstructive sleep apnea

916696

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-29

Identification of novel loci in obstructive sleep apnea in European American and African American children.

Quinlan CM, Chang X et al.

Sleep

Study objectives: To identify genetic susceptibility variants in pediatric obstructive sleep apnea i...

Pediatric obstructive sleep apnea

3853

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-12

Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-Related Traits Identifies Novel Risk Loci in Han Chinese Individuals.

Xu H, Liu F et al.

Am J Respir Crit Care Med

Rationale: Previous genetic studies of obstructive sleep apnea (OSA) have limitations in terms of pr...

Obstructive sleep apnea

20590

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-26

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Cade BE, Lee J et al.

Genome Med

Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic a...

Obstructive sleep apnea trait (apnea hypopnea index)

1942

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-27

Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity.

Liu Y, Zhang X et al.

Int J Obes (Lond)

Background/objectives: Neck circumference, an index of upper airway fat, has been suggested to be an...

Neck circumference

Replicated

16555

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-26

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.

Strausz S, Ruotsalainen S et al.

Eur Respir J

There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea (OSA)....

Obstructive sleep apnea

Replicated

1177519

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-14

Genome-wide association study reveals two novel risk alleles for incident obstructive sleep apnea in the EPISONO cohort.

Farias Tempaku P, Leite Santoro M et al.

Sleep Med

Objective/background: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder that has a...

Obstructive sleep apnea trait (apnea hypopnea index, change over time)

706

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-27

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery.

Cha EDK, Veturi Y et al.

J Obes

The location and type of adipose tissue is an important factor in metabolic syndrome. A database of ...

Subcutaneous adipose tissue

2545

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-27

Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.

Chen H, Cade BE et al.

Am J Respir Cell Mol Biol

Obstructive sleep apnea (OSA) is a common heritable disorder displaying marked sexual dimorphism in ...

Obstructive sleep apnea trait (apnea hypopnea index)

Replicated

19733

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-15

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans.

Cade BE, Chen H et al.

Am J Respir Crit Care Med

Rationale: Obstructive sleep apnea is a common disorder associated with increased risk for cardiovas...

Obstructive sleep apnea trait (apnea hypopnea index)

Replicated

19593

Participants

N/A

Studies

Details PubMed

GWAS 2015-07-01

Associations of Sleep Apnea, NRG1 Polymorphisms, Alcohol Consumption, and Cerebral White Matter Hyperintensities: Analysis with Genome-Wide Association Data.

Baik I, Seo HS et al.

Sleep

Study objective: There are few studies on gene-environment interactions with obstructive sleep apnea...

Obstructive sleep apnea

470

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.

Kurniansyah N, Strausz SJ et al.

EBioMedicine

Obstructive sleep apnea

2025-06-04

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Sofer T, Kurniansyah N et al.

EBioMedicine

Obstructive sleep apnea

2023-03-27

Identification of novel loci in obstructive sleep apnea in European American and African American children.

Quinlan CM, Chang X et al.

Sleep

Pediatric obstructive sleep apnea

2022-07-29

Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-Related Traits Identifies Novel Risk Loci in Han Chinese Individuals.

Xu H, Liu F et al.

Am J Respir Crit Care Med

Obstructive sleep apnea

2022-07-12

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Cade BE, Lee J et al.

Genome Med

Obstructive sleep apnea trait (apnea hypopnea index)

2021-08-26

Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity.

Liu Y, Zhang X et al.

Int J Obes (Lond)

Neck circumference

2021-04-27

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health.

Strausz S, Ruotsalainen S et al.

Eur Respir J

Obstructive sleep apnea

2020-11-26

Genome-wide association study reveals two novel risk alleles for incident obstructive sleep apnea in the EPISONO cohort.

Farias Tempaku P, Leite Santoro M et al.

Sleep Med

Obstructive sleep apnea trait (apnea hypopnea index, change over time)

2019-08-14

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery.

Cha EDK, Veturi Y et al.

J Obes

Subcutaneous adipose tissue

2018-09-27

Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.

Chen H, Cade BE et al.

Am J Respir Cell Mol Biol

Obstructive sleep apnea trait (apnea hypopnea index)

2017-10-27

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans.

Cade BE, Chen H et al.

Am J Respir Crit Care Med

Obstructive sleep apnea trait (apnea hypopnea index)

2016-03-15

Associations of Sleep Apnea, NRG1 Polymorphisms, Alcohol Consumption, and Cerebral White Matter Hyperintensities: Analysis with Genome-Wide Association Data.

Baik I, Seo HS et al.

Sleep

Obstructive sleep apnea

2015-07-01